       Document 0077
 DOCN  M94A0077
 TI    Nutrition: a cofactor in HIV disease.
 DT    9412
 AU    Timbo BB; Tollefson L; Center for Food Safety and Applied Nutrition,
       Food and Drug; Administration, Washington, DC.
 SO    J Am Diet Assoc. 1994 Sep;94(9):1018-22. Unique Identifier : AIDSLINE
       MED/94351122
 AB    The relationships among nutritional status, infectious disease, and the
       immune system suggest that nutrition may be a cofactor in human
       immunodeficiency virus (HIV) progression. We examined nutrition as a
       cofactor in HIV disease by reviewing the current literature on the
       interactions of nutrition, infectious disease processes, and immune
       system dysfunction. Studies demonstrate that poor nutritional status and
       infection affect the immune system and interact with each other. This
       relationship leads to the development of opportunistic infections and
       malignancies, which may result in a diagnosis of acquired
       immunodeficiency syndrome. Moreover, evidence from our review indicates
       that nutritional status may play a role in HIV disease progression. We
       recommend that clinical trials be conducted to evaluate general
       malnutrition and the efficacy of supplementation with specific nutrients
       at various stages of HIV disease.
 DE    Human  HIV Infections/*ETIOLOGY/IMMUNOLOGY  Immune System/*IMMUNOLOGY
       Nutrition Disorders/*COMPLICATIONS  *Nutritional Status  JOURNAL ARTICLE
       REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

