       Document 0587
 DOCN  M9640587
 TI    [Adult HTLV-I positive leukemia-lymphoma in Argentina]
 DT    9604
 AU    Gioseffi ON; Nucifora E; Fantl D; Dufour C; Milone J; Di Paolo H;
       Hospital Nacional Profesor Alejandro Posadas, Prov. de Buenos; Aires,
       Argentina.
 SO    Sangre (Barc). 1995 Oct;40(5):421-4. Unique Identifier : AIDSLINE
       MED/96151813
 AB    Human T-cell lymphotropic virus type I (HTLV-I) is associated with adult
       T-cell leukaemia/lymphoma (ATLL) and tropical spastic paraparesis
       (TSP/HAM) in endemic and non-endemic areas. Serological studies have
       shown that HTLV-I is prevalent in some Latin American countries such as
       Brasil, Chile, Colombia, Peru and Uruguay. We describe here the clinical
       and laboratory features of five cases of ATLL diagnosed in Argentina.
       All patients (4 males, 1 female; median age 48.2 years) were of
       caucasian origin; 4 born in Argentina and 1 in Chile. High risk factors
       for HTLV-I infection were not apparent in Argentina patients, whereas
       the Chilean resident, who was a promiscuous heterosexual, travelled
       through Chile frequently. Positive results for antibodies to HTLV-I were
       detected in all five cases and in some of their relatives. This report
       suggests that HTLV-I infection may be endemic in, Argentina where TSP
       has also been described.
 DE    Adult  Argentina/EPIDEMIOLOGY  English Abstract  Female  Human
       HTLV-I/*IMMUNOLOGY  Leukemia-Lymphoma, T-Cell, Acute,
       HTLV-I-Associated/*EPIDEMIOLOGY/  VIROLOGY  Male  Middle Age  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

