       Document 0629
 DOCN  M9640629
 TI    A review of mechanisms of wasting in HIV disease [see comments]
 DT    9604
 AU    Fields-Gardner C
 SO    Nutr Clin Pract. 1995 Oct;10(5):167-76. Unique Identifier : AIDSLINE
       MED/96153311
 CM    Comment in: Nutr Clin Pract 1995 Oct;10(5):165
 AB    According to estimates, between 50% to 90% of patients infected with the
       Human Immunodeficiency Virus (HIV) will experience some form of
       malnutrition. The degree and types of malnutrition are attributed to
       alterations in nutrient intake, absorption, and metabolism. Causes for
       each of these changes are complex and multifactorial. Research on
       treatment modalities generally concentrates on a single mechanism and
       reports varying degrees of short-term benefit. Appetite stimulation
       along with special diets, oral supplements, and nonvolitional enteral or
       parenteral nutrient provision may improve nutrient intake and body
       weight. Therapies aimed at the rehabilitation and improvement of the
       pool of functioning protein stores, such as alteration of inflammatory
       response, restoration of hormonal balance, and exercise are under
       investigation. Longer term studies will allow researchers to observe
       effects of therapies on overall body functions. With the development of
       clinical standards of care, the maintenance and restoration of
       nutritional status is emerging as the foundation for HIV disease
       management.
 DE    Digestion  Human  HIV Infections/*COMPLICATIONS  Nutrition
       Disorders/METABOLISM/*THERAPY/*VIROLOGY  Nutritional Status  Nutritional
       Support/*METHODS  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

