       Document 0636
 DOCN  M9640636
 TI    Natural history of untreated cytomegalovirus retinitis.
 DT    9604
 AU    Bowen EF; Wilson P; Atkins M; Madge S; Griffiths PD; Johnson MA; Emery
       VC; Department of Virology, Royal Free Hospital School of Medicine,;
       Hampstead, London, UK.
 SO    Lancet. 1995 Dec 23-30;346(8991-8892):1671-3. Unique Identifier :
       AIDSLINE MED/96110604
 AB    Cytomegalovirus infection is common in patients with AIDS, and often
       causes retinitis. Treatment is rarely curative, but the progression of
       retinitis is delayed. The untreated course of cytomegalovirus retinitis
       in AIDS is unknown. We report a 35-year-old man with retinitis who
       refused treatment. Retinitis resulted in blindness within 6 months.
       Measurement of cytomegalovirus genomes showed an increasing viral load
       in blood and urine.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS  Adult
       Blindness/ETIOLOGY  Blood/VIROLOGY  Case Report
       Cytomegalovirus/GENETICS  Cytomegalovirus
       Retinitis/*COMPLICATIONS/VIROLOGY  Genome, Viral  Human  Male  Support,
       Non-U.S. Gov't  Urine/VIROLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

