       Document 0805
 DOCN  M9640805
 TI    Herpesvirus infections in persons infected with human immunodeficiency
       virus.
 DT    9604
 AU    Stewart JA; Reef SE; Pellett PE; Corey L; Whitley RJ; Division of Viral
       and Rickettsial Diseases, Centers for Disease; Control and Prevention,
       Atlanta, Georgia 30333, USA.
 SO    Clin Infect Dis. 1995 Aug;21 Suppl 1:S114-20. Unique Identifier :
       AIDSLINE MED/96002839
 AB    Herpesviruses are among the most common causes of infections of humans.
       Viruses in this family share the unique biological property of being
       able to establish latency and to recur. Furthermore, chronic excretion
       of virus is not uncommon. In the immunocompromised host, including
       persons with human immunodeficiency virus (HIV) infection, herpesvirus
       disease can be particularly severe, resulting in chronic, persistent,
       active infection and, in some cases, life-threatening disease. The most
       pathogenic of the herpesviruses in patients with AIDS include herpes
       simplex viruses, human cytomegalovirus, and varicella-zoster virus.
       Disease caused by Epstein-Barr virus, particularly opportunistic
       malignancies, has been recognized. A new herpesvirus that is associated
       with Kaposi's sarcoma was recently described. On the other hand, disease
       caused by human herpesviruses 6 and 7 in persons infected with HIV
       remains to be unequivocally recognized. Prevention of exposure to
       herpesviruses, disease, and recurrence requires different measures than
       those for some of the other opportunistic infections in HIV-infected
       patients; this is because herpesvirus disease develops in most of these
       individuals as a result of reactivation rather than primary infection.
       Thus, approaches to the prevention and control of herpesvirus infections
       must be individualized according to both the type of virus as well as
       the type of infection (i.e., primary or recurrent). We discuss
       recommended measures for the prevention and control of these infections.
 DE    Herpes Simplex  Herpesviridae Infections/*EPIDEMIOLOGY/PREVENTION &
       CONTROL  Human  HIV Infections/*COMPLICATIONS  Incidence  Recurrence
       Risk Factors  United States/EPIDEMIOLOGY  JOURNAL ARTICLE  REVIEW
       REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

