ChemNovel: The Choice for Novel Molecules

September 1994 -- Chemical Design is pleased to announce the arrival of
ChemNovel, an innovative tool for lead generation, on display for the
first time at the National ACS Meeting in Washington, D.C. The discovery
of new active drugs is vital for pharmaceutical companies. By suggesting
where to start, ChemNovel can save time and money!

Using a description of the structural features required for particular
activity, known as the pharmacophore, ChemNovel invents new molecules in
seconds which meet these requirements. With chemical intuition, ChemNovel
rejects molecules which are impossible to synthesize while those
containing unfavorable components are down-weighted. Compared with the
time-consuming random screening of the past, the benefits to the
pharmaceutical industry are obvious.

ChemNovel is an integral part of New Chem-X, today's solution for new
product research on the desktop. New Chem-X offers a unique integration of
lead generation and lead optimization tools for drug discovery. The same
functionality and accessible user interface is available on all supported
platforms from low cost desktop PC's or Macintoshes, to powerful UNIX
workstations such as Silicon Graphics, IBM RS/6000 and Digital Alpha AXP.

Chemical Design's competitive pricing strategy means New Chem-X continues
to offer excellent value for money. starting with the entry level 2D
database system, Chem-X/BASE, at only $4990 for the desktop PC or
Macintosh, additional modules like ChemDBS-3D for 3D database searching
and automatic pharmacophore identification, and now ChemNovel for
generating novel molecules, may be added at $1000 per module. These
aggressive prices are also applicable to the Apple Macintosh, while New
Chem-X prices for UNIX workstations are only twice those of MS Windows.
Academic discounts of 75% are available.

Chem-X is used by over 600 research sites world-wide, including divisions
of most multi-national pharmaceutical companies. The software is probably
best known for its 3D database pharmacophore searching capabilities where
Chemical Design has demonstrated that its technology is 2 years ahead of
the competition and producing patentable drugs. Chemical Design releases
software updates and offers world-wide telephone support and consultancy
services.

Chemical Design Inc.
200 Route 17 South, Suite 120
Mahwah, NJ 07430
(201) 529-3323,  Fax (201) 529-2443

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