       Document 0286
 DOCN  M9650286
 TI    Usefulness of bone marrow examination in the evaluation of unexplained
       fevers in patients infected with human immunodeficiency virus.
 DT    9605
 AU    Engels E; Marks PW; Kazanjian P; Department of Medicine, Brigham and
       Women's Hospital, Boston,; Massachusetts, USA.
 SO    Clin Infect Dis. 1995 Aug;21(2):427-8. Unique Identifier : AIDSLINE
       MED/96002801
 AB    The diagnostic usefulness of 69 bone marrow examinations (BMEs)
       performed for evaluating unexplained fever in 65 persons who were
       infected with human immunodeficiency virus was retrospectively compared
       with the usefulness of other diagnostic modalities used to investigate
       the cause of fever. An etiology for the fever was identified by BME in
       22 of the 69 cases (diagnostic yield, 32%). In 19 of these 22 cases, the
       same diagnosis had been made by another diagnostic modality, but the
       diagnosis was made by BME as rapidly or sooner in 10 of the 19 cases and
       was made exclusively by BME in the three other cases. We suggest that
       BME is indicated when a diagnosis is urgently sought or when an
       evaluation with other diagnostic modalities has been unsuccessful.
 DE    Bone Marrow/MICROBIOLOGY/*PATHOLOGY  Bone Marrow Examination  Fever of
       Unknown Origin/*ETIOLOGY  Histoplasmosis/*COMPLICATIONS  Human  HIV
       Infections/*COMPLICATIONS  Lymphoma/*COMPLICATIONS  Microbiological
       Techniques  Mycobacterium Infections/*COMPLICATIONS  Retrospective
       Studies  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

