       Document 0069
 DOCN  M9490069
 TI    Seroepidemiological associations between tuberculosis, malaria,
       hepatitis B, and AIDS in West Africa.
 DT    9411
 AU    Adebajo AO; Smith DJ; Hazleman BL; Wreghitt TG; Rheumatology Research
       Unit, Addenbrooke's Hospital, Cambridge,; United Kingdom.
 SO    J Med Virol. 1994 Apr;42(4):366-8. Unique Identifier : AIDSLINE
       MED/94322017
 AB    Serum samples from 51 patients with malaria, 35 patients with hepatitis
       B virus infection, 111 patients with tuberculosis, and 166 healthy
       controls were studied to determine any associations between
       tuberculosis, malaria, hepatitis B, and AIDS in Nigeria, West Africa.
       All serum samples were examined for the presence of HIV-1/HIV-2,
       hepatitis B virus surface antigen (HBsAg), and malaria antibodies. Only
       one patient was HIV-1 antibody-positive and none HIV-2
       antibody-positive. Statistical associations were found between the
       presence of malaria antibody titres on the one hand and a diagnosis of
       hepatitis B virus infection (P < 0.05) or tuberculosis (P < 0.05). A
       stronger association (P < 0.001) was found between the presence of HBsAg
       and tuberculosis suggesting that HBsAg carriers are at higher risk of
       contracting tuberculosis.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adolescence  Adult
       Aged  Aged, 80 and over  Antibodies, Protozoan/BLOOD  Carrier State
       Female  Hepatitis B/*COMPLICATIONS  Hepatitis B Surface
       Antigens/ANALYSIS  Human  HIV Antibodies/BLOOD  Malaria/*COMPLICATIONS
       Male  Middle Age  Risk Factors  Tuberculosis/*COMPLICATIONS  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

