       Document 0597
 DOCN  M9490597
 TI    Pure cutting current for loop excision of squamous intraepithelial
       lesions.
 DT    9411
 AU    McLucas B; McGill J; Department of Obstetrics and Gynecology, University
       of California; at Los Angeles 90024.
 SO    J Reprod Med. 1994 May;39(5):373-6. Unique Identifier : AIDSLINE
       MED/94343353
 AB    Clear margins are critical to the identification of complete excision of
       premalignant lesions on the cervix. Large loop excision of the
       transformation zone aids the pathologic evaluation of the excised
       specimen while it causes minimal thermal damage. Prior studies of loop
       excision were performed with a cutting current blended with a
       coagulating waveform to aid hemostasis. Blended current has higher
       voltage, which may cause tissue to stick to the electrode and produce
       thermal damage to the cervix. In this series, pure cutting current was
       used to excise the cervical transformation zone in 20 patients. The
       depth of thermal damage was studied in 6 patients; the average
       endocervical zone of damage was 0.47 mm and that of the exocervical
       zone, 0.43 mm. The base of the cervix could be examined with the
       colposcope for the presence of glands. None of our procedures was
       complicated by intraoperative or delayed bleeding. The preoperative
       injection of a vasoconstrictor into the cervical stroma is thought to
       aid the surgery by its hemostatic properties.
 DE    Carcinoma, Squamous Cell/PATHOLOGY/*SURGERY  Cervical Intraepithelial
       Neoplasia/PATHOLOGY/*SURGERY  Cervix Neoplasms/PATHOLOGY/*SURGERY
       Colposcopy  Drug Combinations  Electrosurgery/ADVERSE
       EFFECTS/INSTRUMENTATION/*METHODS  Epinephrine/THERAPEUTIC USE  Female
       Follow-Up Studies  Human  Lidocaine/THERAPEUTIC USE  Pilot Projects
       Premedication  Uterine Hemorrhage/EPIDEMIOLOGY/ETIOLOGY  JOURNAL ARTICLE
       REVIEW  REVIEW, MULTICASE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

