       Document 0237
 DOCN  M94A0237
 TI    HIV infection in recipients of blood products from donors with known
       duration of infection.
 DT    9412
 AU    Ashton LJ; Learmont J; Luo K; Wylie B; Stewart G; Kaldor JM; National
       Centre in HIV Epidemiology and Clinical Research,; University of New
       South Wales, Sydney, Australia.
 SO    Lancet. 1994 Sep 10;344(8924):718-20. Unique Identifier : AIDSLINE
       MED/94359315
 AB    From a registry of people with transfusion-acquired HIV infection, 25
       recipients were identified for whom the dates of HIV infection in the 8
       corresponding donors could be established. Longer times to AIDS and to
       death in recipients were independently associated (p < 0.01) with the
       receipt of blood from donors who developed AIDS more than 10 years after
       HIV infection, as well as with older age and fewer transfusions. Sex,
       zidovudine treatment, and severity of illness at transfusion were not
       significantly associated with survival.
 DE    Acquired Immunodeficiency Syndrome/MORTALITY/*PHYSIOPATHOLOGY
       Adolescence  Adult  Blood Component Transfusion/*ADVERSE EFFECTS  *Blood
       Donors  *Blood-Borne Pathogens  Female  Follow-Up Studies  Human  HIV
       Infections/DRUG THERAPY/PHYSIOPATHOLOGY/*TRANSMISSION  Male  Middle Age
       Multivariate Analysis  Prognosis  Support, Non-U.S. Gov't  Survival
       Analysis  Time Factors  Zidovudine/THERAPEUTIC USE  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

