       Document 0240
 DOCN  M94A0240
 TI    [Studies on neurogenic bladder due to human T-lymphotropic virus type-I
       associated myelopathy (HAM)]
 DT    9412
 AU    Imamura A; Department of Urology, Faculty of Medicine, Kagoshima
       University,; Japan.
 SO    Nippon Hinyokika Gakkai Zasshi. 1994 Jul;85(7):1106-15. Unique
       Identifier : AIDSLINE MED/94359091
 AB    Fifty cases of untreated human T-cell lymphotropic virus type I (HTLV-I)
       associated myelopathy (HAM) were evaluated by urodynamic studies to
       clarify the nature of urinary disturbance and to find out suitable
       urological treatment. Both irritative and obstructive symptoms coexisted
       in the HAM patients. 38% of the patients experienced only urinary
       symptoms throughout the affected period. A main cause of frequency was
       detrusor hyperreflexia at filling phase, which was found in 58% of the
       patients. However, decreased effective bladder capacity due to large
       amount of residual urine was possibly an another cause of frequency.
       Detrusor sphincter dyssynergia was the main cause of difficulty of
       urination, but in some cases underactive detrusor at voiding phase was
       also the cause of difficulty of urination. Hydronephrosis was observed
       in only 5 kidneys, although as many as 30 out of 46 cases (65.2%) showed
       bladder deformity. 17 cases (34%) had urinary tract infection at first
       visit. As the activity of daily living was deteriorated, the mean volume
       of residual urine, incidence of detrusor hyperreflexia and detrusor
       sphincter dyssynergia were all increased. Medical treatment was
       effective to relieve subjective symptoms, but urodynamic examination did
       not necessarily review improvement. Intermittent catheterization was
       needed and successful in 64% of all cases. Patients with HAM must be
       carefully followed up by urologists.
 DE    Adult  Aged  Bladder/PHYSIOPATHOLOGY  Bladder,
       Neurogenic/*ETIOLOGY/PHYSIOPATHOLOGY  English Abstract  Female  Human
       Male  Manometry  Middle Age  Paraparesis, Tropical
       Spastic/*COMPLICATIONS  Urodynamics  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

