       Document 2499
 DOCN  M94A2499
 TI    Epidemiology of retroviral infections in south India.
 DT    9412
 AU    Babu PG; Ishida T; Nerurkar V; John TJ; CMC Hosp, Vellore, India.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):290 (abstract no. PC0082). Unique
       Identifier : AIDSLINE ICA10/94370076
 AB    OBJECTIVE: To determine time trends of HIV-1, HIV-2, HTLV-I/II and
       STLV-I infections in Southern India. METHODS: From 1986 onwards, sera
       collected from persons at high risk and low risk for human retroviral
       infections, and from 1982 onwards, locally caught bonnet monkeys, were
       screened for respective antibodies by ELISA/particle agglutination test.
       Reactive samples were confirmed by Western Blot. PCR and virus cultures
       were done where necessary. RESULTS: HIV-1 prevalence increased from 2.5%
       in 1986 to 40% in 1993 in female commercial sex workers, from 0.5% to 5%
       in male STD patients, and from 0.16% to 0.3% in non-professional blood
       donors while it remained stable at 0.04% in pregnant women. HIV-2,
       HTLV-I & II were detected in risk groups in 1990-91. HTLV-I/II has been
       detected in blood donors in 1994. STLV prevalence ranged from 23% to 44%
       during the last decade. DISCUSSION AND CONCLUSIONS: HIV-1 infection is
       spreading rapidly in high risk groups while the spread is slow but
       steady in low risk groups representative of general population. Other
       retroviral infections are also prevalent in our region.
 DE    Animal  Female  Human  HIV Infections/*EPIDEMIOLOGY  HIV-1  HIV-2  HTLV
       Infections/*EPIDEMIOLOGY/VETERINARY  HTLV-I  HTLV-II  India/EPIDEMIOLOGY
       Macaca radiata  Male  Monkey Diseases/EPIDEMIOLOGY  Prevalence  Risk
       Factors  STLV  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

