       Document 2547
 DOCN  M94A2547
 TI    Female genital herpes--22 years' experience in Tokyo.
 DT    9412
 AU    Kawana T; Tokyo University Branch Hospital.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):28 (abstract no. 084B). Unique
       Identifier : AIDSLINE ICA10/94370028
 AB    OBJECTIVE: The purpose of this study is to study female genital herpes
       from clinical and virological viewpoint as well as change of this
       disease during these 22 years. METHODS: More than 500 female genital
       herpes cases were included, who visited our outpatient clinic between
       1971 and 1993. All patients were diagnosed by virus culture. These
       patients were clinically classified as acute, recurrent and provoked
       type. The correlation between clinical type and type of herpes simplex
       virus (HSV) was studied. RESULTS: The number of patients markedly
       increased around 1980 and has been steady since then. Recently recurrent
       type has been gradually increasing. In acute (primary) cases, 61% was
       caused by HSV-1 and remaining 39% by HSV-2. On the other hand, 90% of
       recurrent type was caused by HSV-2. HSV type distribution changed during
       this 22 years. In recent years, 45% of primary female genital herpes was
       caused by HSV-2 where as in 1970s 35% had been caused by HSV-2.
       DISCUSSION AND CONCLUSIONS: Prevalence of female genital herpes has been
       increasing during these 22 years. Recently, genital herpes caused by
       HSV-2 has been increasing, which may result in endemic extension of this
       disease.
 DE    Female  Herpes Genitalis/*EPIDEMIOLOGY/MICROBIOLOGY  Herpesvirus 1,
       Human/ISOLATION & PURIF  Herpesvirus 2, Human/ISOLATION & PURIF  Human
       Japan/EPIDEMIOLOGY  Virus Cultivation  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

