       Document 0016
 DOCN  M9550016
 TI    Otorhinolaryngological aspects of HIV infections: personal experience.
 DT    9505
 AU    Zambetti G; Luce M; Ciofalo A; Leonardi M; Filiaci F; Department of
       Otorhinolaryngology, C.L.O., Rome University, La; Sapienza.
 SO    Allergol Immunopathol (Madr). 1994 Sep-Oct;22(5):192-6. Unique
       Identifier : AIDSLINE MED/95141991
 AB    The involvement of the ENT sphere in HIV infections is fairly common,
       but the relative manifestations, though not to be considered atypical,
       are not pathognomonic. The present study has been set up for the
       otoiatric assessment of a group of HIV patients and the correlation of
       ENT symptoms with the various stages of the disease. To this end, 60
       patients were examined (35 belonged to groups 2-3 and 25 to group 4) of
       whom 50% were drug addicts, 36% homosexuals and 14% heterosexuals. All
       patients underwent a complete ENT examination as well as the assessment
       of hearing and vestibular function, of olfactory and taste functions, of
       respiratory and nasal mucociliary functions along with an anti-HIV
       antibody check of nasal secretion. Results showed a prevalence of
       otologic and rhinosinusal symptoms as well as cervical-facial swelling.
       Testing revealed a hearing loss of mainly conductive origin caused by
       otitis and tubal stenosis; vestibular hyporeflexia; mixed hyposmia and
       hypogeusia owing to the involvement of multiple cranial nerves;
       respiratory and mucociliary changes due to rhinitis and hypertrophy of
       the nasal mucosa. In all cases anti-HIV antibodies were found in nasal
       secretion. From a diagnostic point of view there was a prevalence of
       specific pathologies: oropharyngeal candidosis, stage 4; cervical
       lymphoadenopathy, stages 2-3; chronic rhinosinusitis, nasal vestibulitis
       and nosebleed; mainly chronic otitis media. All such manifestations
       suggest a marked involvement of ENT organs, which can be attributed to
       the anatomical characteristics of the area, with the relative diagnostic
       and prognostic implications of HIV infection.
 DE    Adult  AIDS-Related Opportunistic Infections/EPIDEMIOLOGY  Comorbidity
       Female  Hearing Loss, Partial/EPIDEMIOLOGY  Human  HIV
       Infections/*EPIDEMIOLOGY  Infection/EPIDEMIOLOGY  Lymphoproliferative
       Disorders/EPIDEMIOLOGY  Male  Middle Age  Otorhinolaryngologic
       Diseases/*EPIDEMIOLOGY  Otorhinolaryngologic Neoplasms/EPIDEMIOLOGY
       Risk Factors  JOURNAL ARTICLE  REVIEW  REVIEW, MULTICASE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

