       Document 0453
 DOCN  M9550453
 TI    Comparative analysis of HIV-1 and HIV-2 indeterminate western blot
       patterns.
 DT    9505
 AU    Ayisi NK; Aidoo M; Virology Unit, Noguchi Memorial Institute for Medical
       Research,; University of Ghana, Legon.
 SO    West Afr J Med. 1994 Jul-Sep;13(3):164-7. Unique Identifier : AIDSLINE
       MED/95143180
 AB    A comparison of HIV-1 and HIV-2 indeterminate Western blot patterns of
       Ghanaian sera collected between 1989 and 1990 was made. Antibodies to
       group specific antigen (GAG) gene products were most frequently detected
       both HIV-1 and HIV-2 indeterminate sera. HIV-2 GAG gene product p26 was
       shown to be a non-specific indicator of infection. Antibody to gp120,
       and envelope gene product of HIV-1 never occurred in indeterminate sera
       whereas antibodies to all the envelope gene products of HIV-2 were
       detected in indeterminate sera.
 DE    Blotting, Western/METHODS  Comparative Study  Enzyme-Linked
       Immunosorbent Assay  Ghana/EPIDEMIOLOGY  Human  HIV Antibodies/*BLOOD
       HIV Envelope Protein gp120/IMMUNOLOGY  HIV
       Seropositivity/EPIDEMIOLOGY/*IMMUNOLOGY  *HIV-1/IMMUNOLOGY
       *HIV-2/IMMUNOLOGY  Population Surveillance  Seroepidemiologic Methods
       Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

