       Document 0070
 DOCN  M9580070
 TI    Clinical differences between pulmonary and extrapulmonary tuberculosis:
       a 5-year retrospective study.
 DT    9506
 AU    Antony SJ; Harrell V; Christie JD; Adams HG; Rumley RL; Department of
       Medicine, East Carolina University School of; Medicine, Greenville,
       North Carolina, USA.
 SO    J Natl Med Assoc. 1995 Mar;87(3):187-92. Unique Identifier : AIDSLINE
       MED/95248571
 AB    This article describes the clinical, epidemiologic, laboratory, and
       treatment characteristics of pulmonary tuberculosis (PTB) and
       extrapulmonary tuberculosis (EPTB) in Eastern North Carolina, a
       primarily rural area. The database was obtained for 1988-1992 from the
       University Medical Center of Eastern North Carolina-Pitt County and East
       Carolina University School of Medicine (the tertiary care referral
       center for this region). One hundred thirty-eight culture-positive
       patients were enrolled in the study; 56% were PTB and 44% were EPTB.
       African-American males constituted 59% of the population. Sixty-nine
       percent of the patient base were uninsured. There was a bimodal age
       distribution of < 40 and > 60 years of age. Factors associated with PTB
       (reported as odds ratios) were white males (2.5), diabetes mellitus
       (5.4), and cancer (5.1). Factors associated with EPTB (reported as odds
       ratios) were African-American females, positive human immunodeficiency
       virus (HIV) serology (8.7), low hematocrit (32.6), and elevated alkaline
       phosphatase (199). This study emphasizes that in the latest resurgence
       of tuberculosis, impoverished rural areas, which have been ignored in
       earlier and present control efforts, are important reservoirs of
       disease.
 DE    Adult  Age Distribution  Aged  Comorbidity  Comparative Study  Female
       Human  Incidence  Logistic Models  Male  Middle Age  North
       Carolina/EPIDEMIOLOGY  Retrospective Studies  Risk Factors  Sex
       Distribution  Tuberculosis/*EPIDEMIOLOGY/*PHYSIOPATHOLOGY  Tuberculosis,
       Pulmonary/EPIDEMIOLOGY/PHYSIOPATHOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

