       Document 0189
 DOCN  M9580189
 TI    Experience of HIV disease in a London District General Hospital.
 DT    9506
 AU    Coker RJ; Desmond N; Poznansky M; Smith C; Shafi MS; Bell D; Riordan JF;
       Murphy S; Department of Genitourinary Medicine, Central Middlesex
       Hospital; NHS Trust, London, UK.
 SO    Int J STD AIDS. 1995 Jan-Feb;6(1):47-9. Unique Identifier : AIDSLINE
       MED/95244665
 AB    The aim of this paper is to describe and discuss the experience of HIV
       disease in Central Middlesex Hospital, London up to June 1993. A
       retrospective study of the total number of HIV-positive patients cared
       for was performed. In addition, prospectively collected data as part of
       local epidemiological surveillance from January 1987 to June 1993 on all
       HIV test requests was analysed. Between January 1987 and June 1993 3695
       individuals were tested for HIV-1 antibody at Central Middlesex
       Hospital. Of these, 101 HIV-1 seropositive individuals were identified
       and have attended this District General Hospital. Seven HIV-1
       seropositive individuals were identified from before December 1986.
       Sixty (56%) had acquired their infection heterosexually. Thirty-eight
       (35%) originated from the UK and 47 (44%) from sub-Saharan Africa; the
       remaining 23 (21%) originated from the rest of Europe, South America and
       the Caribbean. Thirty-four (31%) of the patient group developed AIDS
       during follow-up at the hospital and in 26 individuals AIDs developed
       within 2 months of their first positive HIV result. The mean survival of
       20 patients after AIDS-defining diagnoses was 7 months 18 days. This
       unselected group of HIV-1 seropositive patients present late in the
       course of their HIV disease and survival following AIDS is poor.
 DE    Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/MORTALITY  Female
       *Hospitals, General  Human  London  Male  Prospective Studies
       Retrospective Studies  Survival Analysis  JOURNAL ARTICLE

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