       Document 0193
 DOCN  M9580193
 TI    The role of Chlamydia trachomatis in urethritis and urethral symptoms in
       women.
 DT    9506
 AU    Horner PJ; May PE; Thomas BJ; Benton AM; Taylor-Robinson D; Department
       of Genitourinary Medicine, St Mary's Hospital Medical; School, London,
       UK.
 SO    Int J STD AIDS. 1995 Jan-Feb;6(1):31-4. Unique Identifier : AIDSLINE
       MED/95244661
 AB    One hundred and fifty women who attended a genitourinary medicine clinic
       and who required a speculum examination were investigated to determine
       the association between Chlamydia trachomatis and urethral symptoms and
       signs. Those who had taken antibiotics with anti-chlamydial activity
       within 3 months or those who were menstruating, pregnant or using an
       intrauterine contraceptive device were excluded. C. trachomatis
       infection of the urethra, or infection of the urethra and cervix
       together, combined with each separately, were strongly associated with >
       = 5 polymorphonuclear (PMN) leucocytes per high-power field (x 1000) in
       a Gram-stained urethral smear (P < 0.00005 and P < 0.0005,
       respectively). This appeared not to arise from leucocyte contamination
       from the lower genital tract. However, C. trachomatis infection of the
       urethra was not associated with symptoms of dysuria or frequency. In
       conclusion, it seems likely that C. trachomatis infection of the urethra
       in women probably causes urethritis which is usually asymptomatic. Women
       who have objective evidence of urethritis might best be managed by
       appropriate antibiotic therapy and counselling, and advice that partners
       should attend for review.
 DE    Adolescence  Adult  Chlamydia trachomatis/*ISOLATION & PURIF  Chlamydia
       Infections/*MICROBIOLOGY  Female  Human  Middle Age  Urethral
       Diseases/MICROBIOLOGY  Urethritis/ETIOLOGY/*MICROBIOLOGY  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

