       Document 0532
 DOCN  M9590532
 TI    Bronchogenic carcinoma in patients seropositive for human
       immunodeficiency virus.
 DT    9509
 AU    Aaron SD; Warner E; Edelson JD; Department of Medicine, St. Michael's
       Hospital, University of; Toronto, Ontario, Canada.
 SO    Chest. 1994 Aug;106(2):640-2. Unique Identifier : AIDSLINE MED/95292708
 AB    The purpose of this report is to describe an association between
       bronchogenic carcinoma and HIV. Three HIV-seropositive patients are
       described who developed bronchogenic cancer (two large cell, one
       adenocarcinoma) before developing an AIDS-defining illness. A critical
       review of the literature revealed 22 other patients in which the
       association of HIV infection and lung cancer is reported. These patients
       are characterized by a relatively young age at diagnosis (median, 43
       years) and prevalence of the adenocarcinoma subtype (13 of 25 patients).
       Twenty of 21 patients had a history of smoking. Among 21 patients for
       whom data were available, 6 patients (28 percent) had AIDS at time of
       diagnosis of lung cancer while 11 patients (55 percent) did not have
       AIDS or AIDS-related complex at diagnosis.
 DE    Adenocarcinoma/ETIOLOGY  Carcinoma, Bronchogenic/*ETIOLOGY  Carcinoma,
       Large Cell/ETIOLOGY  Case Report  Fatal Outcome  Human  HIV
       Infections/*COMPLICATIONS  Lung Neoplasms/*ETIOLOGY  Male  Middle Age
       JOURNAL ARTICLE  REVIEW  REVIEW OF REPORTED CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

