       Document 0569
 DOCN  M9590569
 TI    Prevalence of human T-cell leukemia virus type 1 (HTLV-I) in adult
       T-cell leukemia (ATL) in non-ATL-endemic Hokkaido of Japan.
 DT    9509
 AU    Iwanaga M; Takada K; Fujiwara S; Oikawa O; Sugiura M; Imai S; Osato T;
       Mikuni C; Maekawa I; Miyazaki T; et al; Department of Virology, Hokkaido
       University School of Medicine,; Sapporo, Japan.
 SO    In Vivo. 1994 Nov-Dec;8(6):1007-10. Unique Identifier : AIDSLINE
       MED/95290633
 AB    Sera and peripheral blood lymphocytes of 40 adult T-cell leukemia (ATL)
       patients in non-ATL-endemic Hokkaido were examined for the prevalence of
       human T-cell leukemia virus type 1 (HTLV-I). All patients had
       HTLV-I-specific antibodies. When the peripheral lymphocytes were
       assessed after short-term cultivation, HTLV-I antigens and virus
       particles were detected. The seroprevalence in 96 cases of non-T-cell
       leukemias and lymphomas and in 30,056 healthy individuals in Hokkaido
       were 3.1% and 0.7%, respectively. HTLV-I seropositive inhabitants of
       Hokkaido can be estimated at about 40,000, and one out of every few
       thousand HTLV-I carriers is likely to develop ATL.
 DE    Human  HTLV-I/IMMUNOLOGY/*ISOLATION & PURIF  HTLV-I Antibodies/ANALYSIS
       HTLV-I Infections/EPIDEMIOLOGY/IMMUNOLOGY/*VIROLOGY  Japan/EPIDEMIOLOGY
       Leukemia, Null-Cell/IMMUNOLOGY/VIROLOGY  Leukemia,
       T-Cell/EPIDEMIOLOGY/IMMUNOLOGY/*VIROLOGY  Prevalence  Support, Non-U.S.
       Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

