       Document 0799
 DOCN  M9590799
 TI    Bronchogenic carcinoma in 13 patients infected with the human
       immunodeficiency virus (HIV): clinical and radiographic findings.
 DT    9509
 AU    Gruden JF; Webb WR; Yao DC; Klein JS; Sandhu JS; Department of
       Radiology, San Francisco General Hospital, CA; 94110, USA.
 SO    J Thorac Imaging. 1995 Spring;10(2):99-105. Unique Identifier : AIDSLINE
       MED/95287426
 AB    Bronchogenic carcinoma is a cause of parenchymal or hilar masses with or
       without mediastinal adenopathy in HIV-seropositive smokers. Lung cancer
       can occur earlier than the more commonly recognized opportunistic
       infections and in patients not known to be HIV seropositive. Tumor cell
       types do not differ markedly from those expected in HIV-seronegative
       young lung cancer patients, but are often poorly differentiated;
       patients with high-grade malignancies fare poorly independent of their
       degree of immunocompromise at diagnosis. Computed tomography (CT) scans
       not only add important information with regard to disease distribution
       and preferred means of diagnosis, but also result in the detection of
       new sites of disease with respect to the plain radiography in many
       patients. Because lung cancer often occurs before the diagnosis of AIDS,
       the association may not be suspected in some cases; poorly
       differentiated, rapidly growing tumors in young smokers may raise the
       suspicion of underlying HIV infection.
 DE    Adult  Carcinoma, Bronchogenic/*COMPLICATIONS/RADIOGRAPHY  Female  Human
       HIV Infections/*COMPLICATIONS  HIV Seropositivity/COMPLICATIONS  Lung
       Neoplasms/*COMPLICATIONS/RADIOGRAPHY  Male  Middle Age  Risk Factors
       Smoking  Tomography, X-Ray Computed  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

