       Document 1096
 DOCN  M9591096
 TI    Tropical spastic paraparesis occurring in HTLV-1 associated infective
       dermatitis. Report of two cases.
 DT    9509
 AU    LaGrenade L; Morgan C; Carberry C; Hanchard B; Fletcher V; Gray R;
       Cranston B; Rodgers-Johnson P; Manns A; Department of Medicine, U.W.I.,
       Jamaica.
 SO    West Indian Med J. 1995 Mar;44(1):34-5. Unique Identifier : AIDSLINE
       MED/95313397
 AB    An association between HTLV-1 infection and infective dermatitis (ID) a
       relapsing eczematous condition of Jamaican children, was reported in
       1990. These patients are at risk of developing other known HTLV-1
       related diseases. We have observed the development of HTLV-1 associated
       myelopathy/tropical spastic paraparesis in two patients, ages 14 and 35
       years, who were diagnosed with ID at ages 2 and 10 years, respectively.
       Infective dermatitis of children serves as an early marker of HTLV-I
       infection and may predict later development of either the malignant
       outcome, adult T-cell leukaemia/lymphoma or the neurologic manifestation
       HAM/TSP among adult carriers of HTLV-1 infection.
 DE    Adolescence  Adult  Case Report  Child, Preschool  Chronic Disease
       Female  Follow-Up Studies  Human  HTLV-I Infections/*DIAGNOSIS  Jamaica
       Paraparesis, Tropical Spastic/*DIAGNOSIS  Skin Diseases,
       Bacterial/*DIAGNOSIS  Staphylococcal Skin Infections/DIAGNOSIS
       Streptococcal Infections/DIAGNOSIS  Support, U.S. Gov't, P.H.S.  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

