       Document 0208
 DOCN  M95A0208
 TI    Isolated peripheral tuberculous lymphadenitis in adults: current
       clinical and diagnostic issues.
 DT    9510
 AU    Artenstein AW; Kim JH; Williams WJ; Chung RC; Division of Retrovirology,
       Walter Reed Army Institute of; Research, Rockville, Maryland 20850, USA.
 SO    Clin Infect Dis. 1995 Apr;20(4):876-82. Unique Identifier : AIDSLINE
       MED/95315391
 AB    Eight cases of isolated peripheral tuberculous lymphadenitis occurred
       over a 16-month period at our institution, prompting a literature review
       to establish the epidemiology, clinical manifestations, and current
       approaches to diagnosis and treatment of this disorder. It occurs most
       commonly in young adult women who either are immigrants from areas where
       tuberculous is endemic or have histories of travel that are suggestive
       of exposure to Mycobacterium tuberculosis. The disease is indolent and
       usually presents as a unilateral painless neck mass. Constitutional
       symptoms are rare, except in individuals infected with the human
       immunodeficiency virus (HIV). The results of skin testing with purified
       protein derivative are invariably positive. Excisional biopsy for
       histopathologic and microbiological evaluations provides the highest
       diagnostic yield, although fine needle aspiration may be useful for
       HIV-infected individuals and in areas of the world with a high
       prevalence of disease. A 6-month course of combination antituberculous
       therapy is adequate for disease due to susceptible organisms. This
       infection may be readily diagnosed if suggestive epidemiological and
       clinical findings lead to expeditious tissue sampling.
 DE    Adult  Algorithms  Case Report  Female  Human  Male  Middle Age
       *Tuberculosis, Lymph Node/DIAGNOSIS/EPIDEMIOLOGY/MICROBIOLOGY  JOURNAL
       ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

