       Document 0219
 DOCN  M95A0219
 TI    Bartonella (Rochalimaea) species as a cause of apparent culture-negative
       endocarditis.
 DT    9510
 AU    Spach DH; Kanter AS; Daniels NA; Nowowiejski DJ; Larson AM; Schmidt RA;
       Swaminathan B; Brenner DJ; Department of Medicine, University of
       Washington Medical Center,; University of Washington School of Medicine,
       Seattle, USA.
 SO    Clin Infect Dis. 1995 Apr;20(4):1044-7. Unique Identifier : AIDSLINE
       MED/95315349
 AB    Bartonella quintana (formerly Rochalimaea quintana) is a recently
       recognized cause of apparent culture-negative endocarditis. We describe
       a 39-year-old, homeless man who developed aortic valve endocarditis
       caused by B. quintana. He had a history of alcoholism and was
       seronegative for the human immunodeficiency virus. We established that
       B. quintana was the cause of the endocarditis on the basis of the
       isolation of B. quintana from blood cultures, the compatibility of
       histochemical stains of cardiac valve tissue, the reactivity of the
       polymerase chain reaction specific for B. quintana on cardiac valve
       tissue, and the failure to isolate an alternative causative organism
       despite extensive efforts. This is the second report of endocarditis
       caused by B. quintana and the fourth report of endocarditis caused by a
       Bartonella species. On the basis of the findings of this report and
       those of other recent reports, further study is warranted to determine
       the overall role of Bartonella species in apparent culture-negative
       endocarditis.
 DE    Adult  *Aortic Valve/MICROBIOLOGY  Bartonella/ISOLATION & PURIF
       *Bartonella Infections/MICROBIOLOGY  Case Report  Endocarditis,
       Bacterial/*MICROBIOLOGY  False Negative Reactions  Heart Valve
       Diseases/MICROBIOLOGY  Human  Male  JOURNAL ARTICLE  REVIEW  REVIEW OF
       REPORTED CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

