       Document 0095
 DOCN  M95B0095
 TI    HIV-1 infection in Juba, southern Sudan.
 DT    9511
 AU    McCarthy MC; Khalid IO; El Tigani A; U.S. Naval Medical Research Unit
       No. 3, Cairo, Egypt.
 SO    J Med Virol. 1995 May;46(1):18-20. Unique Identifier : AIDSLINE
       MED/95348663
 AB    Thirty years of civil war in the Sudan have resulted in the isolation of
       the southern provinces which border Central and East Africa.
       Consequently, little is known about the epidemiology of HIV-1 infection
       in this region. To estimate the prevalence of HIV-1 infection in
       southern Sudan and the risk factors associated with disease
       transmission, a seroepidemiologic survey was conducted in the township
       of Juba. Study subjects invited to participate in this study included
       medical outpatients, inpatients hospitalized for active tuberculosis,
       and female prostitutes. A total of 401 subjects participated in the
       study. HIV-1 infection was confirmed in 25 subjects. The prevalence of
       HIV-1 infection was 19% (8/42) among tuberculosis patients, 16% (8/50)
       among prostitutes, and 3% (9/309) among outpatients. A significantly
       higher prevalence of HIV-1 infection was found among female prostitutes
       when compared to female outpatients: 16% (8/50) vs. 2% (4/178), P <
       0.001. Correspondingly, the prevalence of seropositives was
       significantly higher among male outpatients reporting a history of
       sexual relations with prostitutes during the prior 10 years compared to
       male outpatients denying relations with prostitutes: 14% (5/37) vs. 0%
       (0/94), P = 0.0011. A history of a sexually transmitted disease (STD)
       was also associated with HIV-1 infection among male outpatients. The
       findings of this study indicate that HIV-1 infection is highly prevalent
       in southern Sudan and that prostitutes and their sexual partners
       represent a major reservoir of HIV infection in this population. This
       epidemiologic pattern resembles that seen in the African nations
       neighboring southern Sudan.(ABSTRACT TRUNCATED AT 250 WORDS)
 DE    Adult  Female  Human  HIV Infections/*EPIDEMIOLOGY  *HIV-1  Male
       Prevalence  Prostitution  Risk Factors  Sudan/EPIDEMIOLOGY  Support,
       U.S. Gov't, Non-P.H.S.  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

