       Document 0285
 DOCN  M95B0285
 TI    Chemosensory function and diet in HIV-infected patients.
 DT    9511
 AU    Mattes RD; Wysocki CJ; Graziani A; MacGregor RR; Monell Chemical Senses
       Center, Philadelphia, PA 19104-3308, USA.
 SO    Laryngoscope. 1995 Aug;105(8 Pt 1):862-6. Unique Identifier : AIDSLINE
       MED/95356686
 AB    Alterations of chemosensory function have been noted in human
       immunodeficiency virus (HIV)-infected patients, but their frequency,
       severity, and relationship to diet have not been adequately assessed.
       Odor and taste identification tests and a taste-intensity scaling task
       were administered to 25 men who were HIV-infected but otherwise healthy.
       Responses were compared to those of 49 comparably aged male control
       subjects. Dietary information was obtained by questionnaire. Although
       72% of HIV-infected patients reported some chemosensory alteration, no
       significant differences in taste identification ability or intensity
       ratings were observed between patients and controls. Twelve percent of
       patients had poor odor identification scores, but the group mean was
       similar to that of controls. Neither measured nor self-reported sensory
       indices were significantly related to any variable of health (e.g., HIV
       helper cell (CD4) count, body weight, or body composition), treatment,
       or diet.
 DE    Adult  Case-Control Studies  *Diet  Human  HIV
       Infections/*PHYSIOPATHOLOGY  Male  Prospective Studies  *Smell  Support,
       U.S. Gov't, P.H.S.  *Taste  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

